Custom Enzymes and Inhibitors
Medchemexpress LLC 4,5,6,7-tetrachloroindan-1,3-dione | 30675-13-9 | MFCD00239209 | 283.92 g/mol | C9H2Cl4O2 | 10 MG
TCID (4,5,6,7-tetrachloroindan-1,3-dione) is a small-molecule research inhibitor of ubiquitin C-terminal hydrolase L3 (UCH-L3), used to probe deubiquitinase activity and cell cycle/DNA damage pathways. It is supplied in milligram-scale quantities for biochemical and cellular studies and includes documented solubility and storage recommendations for research use.
- CAS number: 30675-13-9
- Molecular formula: C9H2Cl4O2
- Molecular weight: 283.92 g/mol
- Target: deubiquitinase UCH-L3
- Pack sizes: 1 mg, 5 mg, 10 mg
- In vitro solubility: DMSO 20 mg/mL (may require ultrasonic)
- Storage: powder -20°C (3 years) or 4°C (2 years)
Sigma Aldrich Fine Chemicals Biosciences Paroxetine maleate salt >=98% (HPLC), solid | 64006-44-6 | MFCD01742665 | 50MG
Paroxetine maleate salt >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 445.44 | 64006-44-6 | MFCD01742665 | 50MG
Selleck Chemical LLC Dapagliflozin 5mg 461432-26-8 BMS-512148
Dapagliflozin (BMS-512148) is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 4. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Revvity Health Sciences Inc HTRF Ultrapure SAM cofactor, 22 µmol
HTRF Ultrapure SAM cofactor, 22 µmol
Sigma Aldrich Fine Chemicals Biosciences Aprotinin from bovine lung lyophilized powder, 3-8 TIU/mg solid | 9087-70-1 | MFCD00130541 | 5MG
Aprotinin from bovine lung lyophilized powder, 3-8 TIU/mg solid | Mol Wt: 6511.44 | 9087-70-1 | MFCD00130541 | 5MG
Medchemexpress LLC Mc-val-cit-pab-indibulin | 2055896-95-0 | 95.8% | 945.48 | C50H55ClN9O8 | 5 MG
MC-Val-Cit-PAB-Indibulin is an antibody-drug conjugate (ADC) agent-linker conjugate that couples the MC-Val-Cit-PAB cleavable linker to indibulin for use in ADC research. It is supplied as a solid for research use only and is intended as a building block or payload-linker component for in vitro and in vivo antitumor studies.
- Agent-linker conjugate using indibulin as the cytotoxic payload.
- Molecular formula: C50H55ClN9O8; molecular weight: 945.48.
- High purity around 95.8% as provided by the supplier.
- Physical form: solid, light yellow to brown.
- Soluble in DMSO (125 mg/mL); example in vivo vehicle: 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline.
- Storage: keep sealed away from moisture; -20°C recommended; in solvent, store at -80°C for long-term.
- Intended for research use only and not for clinical or therapeutic use.
Selleck Chemical LLC ABT-751 (E7010) 10mg 141430-65-1
ABT-751 (E7010) binds to the colchicine site on ?-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Saracatinib (AZD0530) 200mg 379231-04-6
Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Saracatinib induces autophagy. Phase 2/3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Posaconazole 5mg 171228-49-2 SCH56592
Posaconazole (SCH56592) is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14? demethylase inhibitor with IC50 of 0.25 ?M. Posaconazole has a median terminal elimination half-life of 15-35 hours. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Sumatriptan succinate United States Pharmacopeia (USP) Reference Standard | 103628-48-4 | MFCD00902856 | 200MG
Sumatriptan succinate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 413.49 | 103628-48-4 | MFCD00902856 | 200MG
Selleck Chemical LLC Saracatinib (AZD0530) 10mg 379231-04-6
Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Saracatinib induces autophagy. Phase 2/3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Barasertib (AZD1152-HQPA) 5mg 722544-51-6 AZD2811
Barasertib (AZD1152-HQPA, AZD2811) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.